Reviewed by Dr. Scott Maymon, ND, NPH, and Dr. Sarah Stone, ND.

If you have been taking semaglutide for several months and are not seeing the weight loss you had hoped, you may be wondering why. There are so many factors that contribute to weight loss, and it can be frustrating when you feel like you are doing everything right but still not seeing results.

Weight loss can be influenced by various factors. In this blog, we will discuss some potential reasons why you may not be losing weight on semaglutide and provide tips on how to overcome these obstacles.

But first, let’s talk about semaglutide and how it works.

What is Semaglutide?

Semaglutide is an injectable medication that is used to treat type 2 diabetes. It belongs to a class of drugs called GLP-1 receptor agonists, which work by mimicking the effects of a hormone called glucagon-like peptide-1 (GLP-1).

GLP-1 helps regulate blood sugar levels and also plays a role in appetite control. Semaglutide works by stimulating the release of insulin and decreasing the release of glucagon, both of which help lower blood sugar levels. It also slows down the movement of food through the stomach, making you feel full for longer periods of time.

Although initially prescribed for type 2 diabetes, semaglutide has also been found to aid in weight loss. In fact, it is now approved by the FDA as a weight loss drug under the brand name Wegovy®.

Now that we have a better understanding of how semaglutide works, let’s explore some possible reasons why you may not be losing weight on this medication.

5 Reasons You May Not Be Losing Weight on Semaglutide

1. Lack of physical activity

While semaglutide can help suppress appetite and regulate blood sugar levels, it is not a magic cure for weight loss. Physical activity is still essential in burning calories and maintaining a healthy body. If you’re not incorporating regular exercise into your routine, this could be hindering your weight loss progress on semaglutide.

2. Unhealthy eating habits

Another factor that could be slowing down your weight loss on semaglutide is unhealthy eating habits. While the medication can help control cravings and reduce appetite, it’s still important to make healthy food choices. 

Simple carbohydrates, sweets, sugars, processed foods and the like are all significant limiting factors in weight loss and overall good health. Eating these foods at night or before bedtime can further exacerbate weight gain. If you’re consuming more calories than your body needs, weight loss will be challenging.

3. Underlying health conditions

Certain medical conditions can make it challenging to lose weight, even with the help of medication. For example, thyroid disorders or polycystic ovary syndrome (PCOS) can affect metabolism and lead to weight gain. 

If you have an underlying medical condition that could be hindering your weight loss progress, consult with your doctor for further guidance. For these reasons, we often encourage full lab work-ups early on to assess underlying health concerns.

4. Medications or supplements

Some medications or supplements may interact with semaglutide and impact its effectiveness in promoting weight loss. It’s important to inform your doctor about all the medications and supplements you are taking before starting semaglutide. They can advise if any adjustments need to be made to ensure the medication works optimally for you.

5. Unrealistic expectations

Weight loss is a journey that takes time and effort. While semaglutide can aid in this process, it’s important to have realistic expectations. Losing weight too quickly can be unhealthy and hard on the body. Expecting dramatic results may also lead to disappointment and frustration if they are not met. Instead, focus on progress rather than perfection, and trust the process.

What To Eat While Taking Semaglutide

While there are no specific dietary restrictions while taking semaglutide, it’s important to make healthy food choices to support weight loss.

A balanced diet includes:

  • Lean protein sources such as chicken, fish, and lean meats
  • Good sources of fiber and plenty of water for hydration
  • A variety of fruits and vegetables for essential vitamins and minerals
  • Healthy fats like avocados, nuts, and olive oil

Be aware of portion sizes and try to limit processed and fatty foods, sugary beverages, and excessive alcohol consumption. It’s also helpful to plan meals and snacks ahead of time to avoid impulsive food choices that may hinder weight loss progress.

Incorporate Physical Activity

Regular physical activity will help you to burn calories, strengthen your muscles, and support overall health. Aim for at least 30 minutes of moderate to vigorous exercise most days of the week. This can include activities like brisk walking, jogging, cycling, or strength training. Find an activity that you enjoy and make it a part of your routine.

You may also find it helpful to consult with a personal trainer or join a fitness class for guidance and accountability. Remember to always listen to your body and start slow if you are new to exercise.

How To Get Through a Weight Loss Plateau on Semaglutide

If you have been consistently following a healthy diet and exercise routine but have hit a weight loss plateau, don’t get discouraged. Weight loss plateaus are common and can happen for various reasons, including metabolic adaptation or hormonal changes. 

Here are some tips to help break through a weight loss stall:

  • Try increasing the intensity or duration of your workouts
  • Re-evaluate your food choices and make sure you are staying within your recommended calorie intake
  • Incorporate more high-fiber foods into your diet, such as fruits, vegetables, and whole grains

Pure Body Health-Your Weight Loss Partner

We understand the struggles of weight loss and are here to support you on your journey. Our team will monitor your progress, provide guidance on healthy eating habits and exercise routines, and offer emotional support along the way. 

Don’t give up if you’re not seeing immediate results on semaglutide – with the right approach, you can reach your weight loss goals.

If you are not currently on semaglutide and are looking for a semaglutide provider, contact Pure Body Health at (480) 427-0442 or complete the online inquiry form. Dr. Sarah Stone, ND, and Dr. Scott Maymon, ND, MPH, will help you navigate your weight loss journey with semaglutide and provide personalized care to achieve your goals.

Remember, sustainable weight loss takes time and effort, but with the right support, it is possible!

Additional Resources

How Vitamins, Supplements, and IV Therapy Can Help With Weight Loss

Weight Loss Aids: Body Contouring and Peptide Therapy

Discover Naturopathic Weight Loss: Lose Weight Nature’s Way

FAQs About Semaglutide and Weight Loss

Can I stop taking semaglutide once I reach my weight loss goal?

It is not recommended to stop taking semaglutide abruptly, as this could lead to a sudden increase in appetite and weight regain. Consult with your doctor before making any changes to your medication regimen.

Can I take semaglutide without making any lifestyle changes?

While semaglutide can aid in weight loss, it is not a substitute for healthy eating and exercise. It is important to make lifestyle changes to support long-term weight management.

How soon can I expect to see results on semaglutide?

Results may vary, but most people start seeing significant weight loss within the first 8-12 weeks of starting semaglutide. Consistency with medication, diet, and exercise is crucial for optimal results.

Will semaglutide help address hormonal imbalances that affect my body weight?

Semaglutide can assist in weight loss efforts by regulating appetite and promoting a feeling of fullness, which can help you achieve a healthier body weight. However, if you have hormonal imbalances such as those caused by PCOS or thyroid disorders, it is important to address these conditions alongside your semaglutide treatment. Consult with your doctor to create a comprehensive plan that includes both medication and strategies to manage hormonal imbalances.

Can stress and lack of sleep impact my results with semaglutide?

Yes, stress and lack of sleep can negatively affect your weight loss efforts. Both can lead to hormonal imbalances that influence body weight and appetite. Managing stress through relaxation techniques and ensuring adequate sleep are vital components of a healthy lifestyle that will complement the effectiveness of semaglutide.